Our bioanalytical capabilities are a key component of the extensive contract services we offer our clients. MRL provides analysis of biological samples generated from pharmacokinetic studies using LC-MS-MS technique. MRL can also help in the interpretation of pharmacokinetic data.

MRL offers assessment of key drug parameters such as:

• Drug-protein binding employing equilibrium dialysis
• Drug permeability using Parallel Artificial MembranePermeability Assay
• Drug metabolic stability using liver microsomes/S9 preparations

(All assays are designed to work in conjunction with LC-MS technique ensuring high sensitivity and specificity.)

MRL Bioanalytical Methods include:

• Limulus amebocyte lysate testing (LAL)
• Enzyme-linked immunosorbent assay (ELISA)
• SDS-PAGE
• Western blot (a.k.a. Protein immunoblot)

For our instrumental capabilities please click here.